Functional Dyspepsia

Functional gastrointestinal disorder (FGID) is the most common disorder affecting the gut affecting up to 40% people in the world.  The disorder is a combination of abnormal motility and sensitivity of the nerves of the intestine as well as altered gut flora and immune system.  The good news is there are NO structural abnormalities that can be seen by blood tests, endoscopy or X-ray. 


Patients have the following symptoms in varying degree;

  • abdominal pain
  • dysphagia (difficulty swallowing)
  • dyspepsia or burning sensation
  • feeling of fullness (early satiety)
  • bloating 
  • diarrhoea
  • constipation

Terminology of the Condition

According to the ROME IV classification of FGID, Functional Dyspepsia is the term referring to patients with postprandial distress syndrome (PDS) and epigastric pain syndrome (EPS).  In general, PDS is a postprandial syndrome while EPS is not but there is a degree of overlap between the 2 conditions.

Management of Functional Dyspepsia

Management of functional dyspepsia is recommended along the following guidelines; 

1. Conservative Treatment

2. Medication

  • Pro-kinetic medications such as Itopride (Ganaton), Cisapride (Propulsid) or Metoclopramide which promotes gastric motility and improves gastro-duodenal coordination can provide symptomatic relief after around 7-10 days of use.  Some side effects of pro-kinetic medications include abdominal cramps, nausea or vomiting, diarrhoea, mood change and drowsiness.
  • Proton pump inhibitors (PPIs) are medications which reduce the production of acid such as Lansoprazole (Prevacid), Rabeprazole (Pariet), Pantoprazole (Controloc), Esomeprazole (Nexium) and Dexlansoprazole (Dexilant).  The most common side effects (usually mild and therefore easily tolerated) of PPIs are headache, diarrhoea or constipation, flatulence, nausea or vomiting and rashes.  

Your doctor may recommend to use the lowest doses and shortest duration of treatment necessary for the condition to reduce the side effects.  

Click to view MayoClinic video on Functional Dyspepsia


Functional dyspepsia is associated with a lot of disturbing symptoms which can affect the quality of patient’s life.  As the root cause of these disorders is still incompletely understood there remains no cure for them.  Nonetheless, most patients get some form of relief from the treatment described above.

Discuss the treatment options with your Pharmacist or Doctor

Disclaimer. TELEME blog posts contains general information about health conditions and treatments. It is not intended to be a substitute for professional medical advice, diagnosis or treatment. The information is not advice and should not be treated as such. 

If you think you may be suffering from any medical condition, you should seek immediate medical attention from your doctor or other professional healthcare providers. You should never delay seeking medical advice, disregard medical advice, or discontinue medical treatment because of information on this website.

How useful was this post?

Click on a star to rate it!

Average rating / 5. Vote count:

No votes so far! Be the first to rate this post.

As you found this post useful...

Share it on social media!

We are sorry that this post was not useful for you!

Let us improve this post!

Tell us how we can improve this post?