Updated on September 22, 2021

A Genetic Variant Test Can Help to Improve Your Heart Health By Gene Express Sdn Bhd

According to the World Health Organisation (WHO), cardiovascular disease is the number one cause of death globally. More people die annually from this disease than from any other cause. Cardiovascular disease can refer to a number of conditions including heart attack, stroke, cerebrovascular disease, and heart valve problems.

Cardiovascular health is normally monitored via blood pressure, body mass index, fasting plasma glucose level, fasting serum cholesterol level, dietary intake, physical activity, and lifestyle choices (healthy vs unhealthy, e.g., tobacco use, alcohol consumption, drug usage, etc).

With advances in genetics and genomics, we now know that certain gene variants (i.e., SNPs, single nucleotide polymorphisms) are linked with:

  • potential risk factors associated with cardiovascular illness and pathology,
  • irregular heart rhythm, the risk of heart disease, and certain environmental factors such as stress and caffeine on the heart, and
  • potential genetic cholesterol issues.

The “Heart Health Module” of Gene Express Heart and Wellness Package determines and analyses the SNPs or variants of 23 genes that affect heart health classified under the following 5 parameters:

ParameterGeneRisk Level
Irregular heart rateMIR297, PITX2, GRK5Low or Increased
Genetic high blood pressureCPLX3, PPARGC1A, MIR297, PITX2, GRK5APOA5, ADRB2, ADD1, MTHFRLow, Normal, Increased, or High
Salt causing high blood pressureADD1Low, Increased, or High
Cholesterol LDL/HDL imbalanceABCG8, PLTP, NUTF2No, Increased, or High
Cardiovascular health issuesCDKN2A, CDKN2B, CDKN2BAS, R451Q, MTHFD1L, APOE, SEZ6L, MIA3, CXCL12, SMAD3Low, Normal, Increased, or High

Knowing your gene variants means that you can know the estimated risk levels of your heart health traits affected by the respective sets of genes mentioned above and can then customize your prevention or mitigation plan.

Click to view Gene Express video on Why DNA Testing?

You will receive five actionable personalised reports with personalized recommendations. The insights are thoroughly explained and the reports provide scientific references

Hence, the results can

  • influence a decision to remove or alter dosages of potential stimulants,
  • be useful to change exercises to potentially improve blood pressure and
    help with exercise choices that may increase blood pressure, and
  • help you to confidently plan a personalised “cardiac diet” (heart healthy diet).

You are empowered to take guided informed actions to achieve your health and fitness goals by staying healthy, improving your health and wellbeing, and reducing health risks.

Discuss your genetic health with a Counsellor or Consultant

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Disclaimer. TELEME blog posts contains general information about health conditions and treatments. It is not intended to be a substitute for professional medical advice, diagnosis or treatment. The information is not advice and should not be treated as such. 

If you think you may be suffering from any medical condition, you should seek immediate medical attention from your doctor or other professional healthcare providers. You should never delay seeking medical advice, disregard medical advice, or discontinue medical treatment because of information on this website.

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